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Old 06-28-19, 02:24 PM
PI-ADHD 29 PI-ADHD 29 is offline
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Re: Concerta;every day or some days for not to develop tolerance?

I've taken 54 mg concerta for four days. It's effect decreased day by day. Even though I intended to go on to use. But i've found an article ( In brief according to it methylphenidate caused a significant loss of dopamine neurons in mice in long term. I know mice and human are very similar generally but also may be different. But i'm in doubt and so took a break.
What do you think about this article?
Born in 1989. Treated for major depression and anxiety since 21 yo.
Tried almost all of SSRI's (none of them worked)
Predominantly inattentive adhd, diagnosed in 2018.
Started with ritalin (worked only for two weeks)
Also tried wellbutrin and strattera
Now: ritalin and medikinet
For about three years local corticosteroid pomades for atopic dermatitis.
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